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Human CA14/Carbonic Anhydrase XIV Protein (CA4-HM214)

ArtNr CA4-HM214-100UG
Hersteller KactusBio
Menge 100 ug
Quantity options 100 ug 500 ug
Kategorie
Format Liquid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag C-hFc
Purity > 95% as determined by Bis-Tris PAGE
Dry ice Yes
Sequence Ala16-Met290
Alias Carbonic anhydrase 14,EC:4.2.1.1,CA-XIV
Versandbedingung Trockeneis
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Targets
CA14/Carbonic Anhydrase XIV
Shipping Temperature
Shipped with dry ice.
Storage Conditions
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight
The protein has a predicted MW of 56.76 kDa. Due to glycosylation, the protein migrates to 65-85 kDa based on Bis-Tris PAGE result.
Description
Recombinant Human CA14/Carbonic Anhydrase XIV Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Ala16-Met290.
Background
Carbonic anhydrase XIV (CA XIV), a transmembrane protein, highly expressed in the central nervous system, is difficult to recombinantly express and purify in large scale for the measurements of inhibitor binding and drug design. CA XIV belongs to the family of twelve catalytically active CA isoforms in the human body. Disorders in the expression of CA XIV cause serious diseases and CA XIV has been described as a possible drug target for the treatment of epilepsy, some retinopathies, and skin tumors.
Endotoxin
Less than 0.1 EU per μg by the LAL method.
Formulation
Supplied as 0.22 μm filtered solution in 20mM Tris, 150mM NaCl (pH 7.5).
Biotinylated
no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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