Antibodies

Mouse Anti-Human MPO mAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Isotype IgG1
Menge 250 ug
Host Mouse
ArtNr CS-CMM122B
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Description
Human Myeloperoxidase (MPO) is a peroxidase enzyme most abundantly present in neutrophil granulocytes (a subtype of white blood cells). It is a lysosomal protein stored in azurophilic granules of the neutrophil. MPO produces hypochlorous acid (HOCl) from hydrogen peroxide (H2O2) and chloride anion (Cl-) (or the equivalent from a non-chlorine halide) during the respiratory burst of a neutrophil. It requires Heme as a cofactor, which causes its green color in secretions rich in neutrophils. Furthermore, it oxidizes tyrosine to tyrosyl radical using hydrogen peroxide as oxidizing agent. Hypochlorous acid and tyrosyl radical are cytotoxic, so they are used by the neutrophil to kill bacteria and other pathogens.
Formulation
PBS pH7.2 + 50% glycerol
Immunogen
Human MPO from Neutrophils
Purification
Protein G Affinity Purified
Storage and Stability
Store below -20C.
Menge: 250 ug
Lieferbar: In stock
Listenpreis: 941,18 €
Preis: 941,18 €
lieferbar

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