Antibodies

Mouse Anti-Human TLR2 Clone BV31-9 mAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Clon BV31-9
Isotype IgG1
Applikationen WB
Menge 100 ul
Host Mouse
ArtNr CS-CMT158
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Western Blot
Description
Mouse Anti-Human TLR2 Clone BV31-9 monoclonal antibody. The Toll-like receptor (TLR) family in mammalia comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL1 receptor motif in the cytoplasmic domain. Up-to-date, ten TLRs (TLR1-10) have been described. TLR2 is differentially expressed in human cells. CD14+ monocytes expressed the highest level of TLR2 followed by CD15+ granulocytes, and CD19+ B-cells. CD3+ T-cells and CD56+ NK cells did not express TLR2. The expression of TLR2 on different cell types are regulated by different immune response modifiers. For example, LPS, GM-CSF, IL1, and IL10 up regulate TLR2, whereas IL4, IFN-gamma, and TNF down regulate TLR2 expression in monocytes.
Formulation
Liquid in PBS, pH 7.2 + 50% glycerol + 1% BSA + 0.02% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Human TLR2
Immunogen
Recombinant human TLR2
Purification
Protein G purified
Storage and Stability
Store at -20C. For long term storage, aliquot and store at -80C. Avoid repeated freeze-thaw cycles.

Arbeitsanleitung

CS-CMT158.pdf

Menge: 100 ul
Lieferbar: In stock
Listenpreis: 780,52 €
Preis: 780,52 €
lieferbar

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