Antibodies

Anti-Human Lactoferrin pAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Menge 5.0 ml
Host Rabbit
ArtNr CS-CPL106A
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Description
Rabbit Anti-human lactoferrin forms a single precipitin arc against human lactoferrin by immunoelectrophoresis. Human Lactoferrin is an iron-binding glycoprotein that facilitates the production of hydroxyl radicals and chelates iron, preventing its accessibility to microorganisms and thus inhibiting growth. Human Lactoferrin is found in secondary granules in polymorphonuclear neutrophils. Human Lactoferrin from human neutrophil(s) lacks terminal fucose residues in the glycan chains that are required for binding to macrophages. Human Lactoferrin plays an important role in iron transport and utilization in humans. A glycoprotein containing about 6% sugar and having a total molecular weight of about 77 kDa, human lactoferrin is capable of binding two ferric ions with high affinity. Although lactoferrin binds iron tightly, the binding is reversible so that the metal is available upon demand to cells with a need for this essential element. Each human lactoferrin molecule has two iron-binding domains. Human Lactoferrin appears to activate host defense systems in part by stimulating the release of interleukin-8, a neutrophil activator.
Formulation
Liquid in a buffer of PBS, pH 7.2.
Specificity
Human Lactoferrin. The anti-human lactoferrin was solid phase absorbed against human serum to ensure specificity.
Immunogen
Human Lactoferrin
Storage and Stability
Store at 2-4C.
Cross-Reactivity
No known reaction to other human proteins.
Menge: 5.0 ml
Lieferbar: In stock
Listenpreis: 574,27 €
Preis: 574,27 €
lieferbar

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