Rabbit Anti-Human Wnt-1 Affinity Purified pAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Human
Isotype IgG
Applikationen WB
Menge 100 ug
Host Rabbit
ArtNr CS-CPW100
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Western Blot Immunohistochemistry
Description
Wnt gene family members including WNT1 through WNT10, play a key role in regulating cellular growth and differentiation. WNT1 is a cysteine-rich, secreted glycoprotein that associates with cell membranes and likely functions as a key regulator of cellular adhesion. WNT1, which is essential for normal development of the embryonic nervous system, contributes to hyperplasia and tumorigenic progression when improperly expressed in mammary tissue. WNT3 is also involved in tumorigenesis and WNT2 and WNT4 may be associated with abnormal proliferation in human breast tissue. WNT1, WNT3, and WNT10b have been implicated along with FGF3 in the development of mouse mammary tumor virus induced mouse mammary carcinomas.
Formulation
Liquid in PBS + 30% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Specificity
Recognizes 41 kDa of human WNT1
Immunogen
Synthetic peptide surrounding amino acid 31 of human WNT1
Purification
Biospecific affinity chromatography
Storage and Stability
Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.

Arbeitsanleitung

CS-CPW100.pdf

Menge: 100 ug
Lieferbar: In stock
Listenpreis: 659,19 €
Preis: 659,19 €
lieferbar

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Arne Pelz

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