Antibodies

Rat Anti-Mouse IFN-beta Clone RMMB-1 FITC mAb

Hersteller Cell Sciences
Kategorie
Typ Antibody
Specific against Mouse
Clon RMMB-1
Isotype IgG1
Applikationen FC
Menge 25 ug
Host Rat
ArtNr CS-CMI230
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Applications
Flow Cytometry, Immunohistochemistry
Description
IFN beta is involved in the regulation of unspecific humoral immune responses and immune responses against viral infections. IFN beta increases the expression of HLA class 1 antigens and blocks the expression of HLA class 2 antigens stimulated by IFN gamma. IFN beta stimulates the activity of NK-cells and hence also antibody-dependent cytotoxicity. The activity of T suppressor cells elicited by several stimuli is stimulated also by IFN beta. IFN beta enhances the synthesis of the low affinity IgE receptor CD23. In activated monocytes, IFN beta induces the synthesis of neopterin. It also enhances serum concentrations of Beta-2-Microglobulin. IFN beta selectively inhibits the expression of some mitochondrial genes. IFN beta shows antiproliferative activity against a number of cell lines established from solid tumors.
Formulation
Phosphate-buffered saline (PBS) pH7.2 + 1% BSA + 0.05% Kathon as a preservative
Immunogen
Mouse IFN beta
Storage and Stability
Store at 2-4C. DO NOT FREEZE. 2 years.
Concentration
0.2 ug/uL
Application Notes
Flow Cytometry: 10 iL is sufficient for labeling of 1x106 cells in 100 iL total volume.It is recommended that each investigator determine appropriate dilutions for individual use.
Menge: 25 ug
Lieferbar: In stock
Listenpreis: 582,72 €
Preis: 582,72 €
lieferbar

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Arbeitsanleitung

CS-CMI230.pdf