Human IL-11 ELISA Kit

Hersteller Cell Sciences
Typ Elisa-Kit
Specific against Human
Menge 1 Plate
ArtNr CS-CKH153
eClass 6.1 32160605
eClass 9.0 32160605
Interleukin-11 (IL11) is a protein that in humans is encoded by the IL11 gene. IL11 is a multifunctional cytokine first isolated from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 is a 23 kDa protein and a member of the IL6-type cytokine family, distinguished based on their use of the common co-receptor gp130. These cytokines drive the assembly of multi-subunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). Signal specificity is provided by the IL11R alpha subunit. IL11 is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B-cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. The Human IL11 ELISA is an, in vitro, enzyme-linked immunosorbent assay for the quantitative measurement of Human IL11 in serum, plasma, cell culture supernatants and urine. This assay employs an antibody specific for Human IL11 coated on a 96-well plate. Standards and samples are pipetted into the wells and IL11 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and Biotinylated Anti-Human IL11 antibody is added. After washing away unbound Biotinylated antibody, HRP-Streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of IL11 bound.
Storage and Stability
May be stored for up to 6 months at 2-8C from the date of shipment. Standard should be stored below -20C (-80C recommended) after reconstitution. Opened Microplate Wells and reagents may be store for up to 1 month at 2-4C. Return unused wells to the pouch containing desiccant pack, reseal along entire edge of zipseal.
The minimum detectable dose of IL11 is typically less than 3 pg/mL.
Menge: 1 Plate
Lieferbar: Out of stock
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