Recombinant Bovine IGFBP2 Receptor Grade

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Bovine
Menge 20 ug
ArtNr CS-BP2A1U020
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Description
Bovine Insulin-like Growth Factor Binding Protein-2 (bIGFBP-2) is a 284 amino acid protein that is one of the six iclassicali IGF binding proteins that play an important role in stabilizing and regulating the activity of IGFs in vivo. Bovine IGFBP-2 binds both human and Bovine IGF-I and IGF-II and modifies their biological activity and bioavailability. Recombinant Bovine IGFBP-2 is available in both Animal/Media Grade (MG) and Receptor Grade (RG). The Animal/Media Grade (MG) product contains mature Bovine IGFBP-2 of correct Molecular Weight as the major species. As a result of alternative processing by the CHO cells used for the Bovine IGFBP-2 production, three other minor Bovine IGFBP-2 isoforms are also present: 1) One with a three amino acid C-terminal deletion, denoted Des (1-3) Bovine IGFBP-2. 2) One with a single amino acid N-terminal extension, denoted A-Bovine IGFBP-2. 3) One with a four amino acid N-terminal extension, denoted GARA-Bovine IGFBP-2. The Bovine IGFBP-2 and GARA-Bovine IGFBP-2 have been further purified from the Animal/Media Grade (MG) to yield Receptor Grade (RG) products.
Source
Produced recombinantly in mammalian cells. Purified by affinity and other chromatographic steps.
Molecular Weight
30.776 kDa - confirmed by Mass Spectometry
Purity
Greater than 95% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per ug (1EU/ug).
Biological Activity
IGF-I Binding Assay : ED50 < 10 nM
Format
Lyophilized

Arbeitsanleitung

CS-BP2A1U020.pdf

Menge: 20 ug
Lieferbar: In stock
Listenpreis: 543,94 €
Preis: 543,94 €
lieferbar

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Ihr Ansprechpartner:

Arne Pelz

sales@hoelzel.de