Recombinant Bovine Aprotinin/BPTI

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Bovine
Menge 20 mg
ArtNr CS-CRA135B
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Description
Recombinant Bovine Aprotinin is designed specifically for cell culture applications, protein purification, diagnostic testing and pharmaceuticals. It is produced in maize without the use of animal or human derived materials and is therefore free from the risk of contaminating human or animal derived viruses or prions. Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. Aprotinin is present in blood and in most tissues, with a high concentration in lung. Aprotinin inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, aprotinin reduces glycoprotein loss (e.g. GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins (e.g. CD11b).
Formulation
Lyophilized from a sterile filtered solution without additives
Reconstitution
Centrifuge vial prior to opening. First add sterile distilled water to the vial to fully solubilize the protein to a concentration not less than 100 ug/ml. After complete solubilization of the protein, it can be further diluted to other aqueous solutions.
Storage and Stability
Store lyophilized protein at 2-4C.
GeneID
404172
Source
Maize (corn)
Molecular Weight
6.51 kDa
Purity
> 90.0% as determined by gel electrophoresis
Protein Accession No
P00974
Endotoxin Level
< 0.1 ng/ug of Aprotinin
Biological Activity
4.6 TIU/mg. One Trypsin inhibitory unit (TIU) is equal to the amount of the inhibitor with the ability to inhibit two trypsin units by 50% where one trypsin unit will hydrolyze 1.0 mmole of N-alpha-benzoyl-DL-Arginine-p-Nitroanilide (BAPNA) per minute at pH 7.8 at 25oC.

Arbeitsanleitung

CS-CRA135B.pdf

Menge: 20 mg
Lieferbar: Out of stock
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