Native Chicken Alpha Actinin 1

Hersteller Cell Sciences
Typ Proteins
Specific against Gallus
Menge 1.0 mg
Host Chicken
ArtNr CS-CRA111C
eClass 6.1 34160400
eClass 9.0 42020190
ACTN1 encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.
The protein was lyophilized from a 1mg/ml solution containing 10 mM Tris acetate buffer pH 7.6 + 0.1 mM EDTA + 2 mM DTT, and 20 mM NaCl.
Storage and Stability
Lyophilized a-Actinin although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution a-Actinin should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Chicken Gizzard.
Molecular Weight
Ultra pure Alpha Actinin having a MW = 95 kDa
Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Menge: 1.0 mg
Lieferbar: Out of stock
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