Recombinant Human proIGF2 (aa 1-156) Receptor Grade

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Human
Menge 20 ug
Host E.coli
ArtNr CS-AHU020
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Description
Recombinant Human Insulin-like Growth Factor-II (Human IGF-II) is synthesized as a 156 amino acid precursor protein, known as proIGF-II. This protein includes an 87 amino acid C-terminal region known as the E-domain. A proteolysis step releases the mature 67 amino acid IGF-II polypeptide. The proIGF-II proteins make up 10-20% of circulating IGF-II. Pro-IGF-II proteins are secreted by some tumor cell lines and levels are elevated in non-islet cell tumor hypoglycemia.
Formulation
Lyophilized white powder. Dried from 0.1 M acetic acid and stored under dry nitrogen at a slight vacuum (-25 kPa)
Reconstitution
Protocol #1000
Storage and Stability
This lyophilized preparation is stable at 2-4C, but should be kept desiccated at -20C for long term storage. Upon reconstitution, the preparation is stable for up to one week at 2-4C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -80C. Avoid repeated freeze/thaw cycles.
GeneID
3481
Source
E. coli
Molecular Weight
The final product contains three major isoforms of proIGF-II corresponding to molecular weights of 16.1, 17.0 and 17.6 kDa. These species correspond to the full length 156 amino acid protein and two smaller species corresponding to C-terminal truncations of approximately 5 and 15 residues which result from the purification process
Purity
> 85% (determined by HPLC and N-terminal sequence analysis)
Endotoxin Level
< 0.1 EU/ug
Biological Activity
Stimulation of protein synthesis in rat L6 myoblasts.
AA Sequence
5 residues > 85 % single sequence

Arbeitsanleitung

CS-AHU020.pdf

Menge: 20 ug
Lieferbar: In stock
Listenpreis: 368,02 €
Preis: 368,02 €
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