Recombinant Human IGF1 (Ala31/Leu60) Receptor Grade

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Human
Menge 20 ug
Host E.coli
ArtNr CS-ALU020
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Description
Human [Ala31][Leu60]Insulin-like Growth Factor-I ([Ala31][Leu60]IGF-I) is an analog of human IGF-I which has an Ala substitution in place of Tyr at position 31 and a Leu substitution in place of Tyr at position 60 of the human IGF-I sequence. [Ala31][Leu60]IGF-I has greatly reduced binding to the Type 1 IGF receptor and to the insulin receptor compared to IGF-I, [Leu24]IGF-I and [Leu60]IGF-I. However [Ala31][Leu60] IGF-I has normal binding to acid-stripped human serum binding proteins. Consequently [Ala31][Leu60]IGF-I is an extremely useful analog of IGF-I for investigating IGF actions largely independent of binding to the Type 1 IGF receptor.
Source
E. coli
Purity
Greater than 95% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per ug (1EU/ug).
Biological Activity
Type 1 IGF receptor binding assay: ED50 Greater than 750 ng/ml. IGF binding protein assay: ED50 Less than 10 ng/ml
Format
Lyophilized
Menge: 20 ug
Lieferbar: In stock
Listenpreis: 368,02 €
Preis: 368,02 €
lieferbar

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