Recombinant Human Annexin A9 (aa 1-338) T7

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Human
Menge 10 ug
Host E.coli
ArtNr CS-CRA121B
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Description
The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. The most striking feature of annexin A9 is a complete ablation of all four homologous type II calcium-binding sites in the conserved tetrad core. Although all 4 type II calcium-binding sites in annexin A9 contained amino acid substitutions that ablated their function, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact. Recombinant Human Annexin A9 is a non-glycosylated, polypeptide chain containing amino acids 1-338 and a T7 tag at the N-terminus. It is purified by proprietary chromatographic techniques
Formulation
Sterile filtered liquid in 10 mM Tris, pH 8.0 + 0.1% Triton X-100 + 0.002% sodium azide. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.
Storage and Stability
Annexin-9 although stable at 2-4C for 1 week, should be stored desiccated at -20C to -80C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please note that the addition of any carrier protein into this product may produce unwanted endotoxin. This depends upon the particular application employed. Avoid repeated freeze-thaw cycles.
GeneID
8416
Source
E. coli
Molecular Weight
38.9 kDa
Purity
> 95% as determined by SDS-PAGE analysis
Protein Accession No
O76027.3
Endotoxin Level
< 0.1 ng/ug of Annexin 9

Arbeitsanleitung

CS-CRA121B.pdf

Menge: 10 ug
Lieferbar: In stock
Listenpreis: 428,68 €
Preis: 428,68 €
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