Native Human Cancer Antigen 15-3

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Human
Menge 25 KU
Host Human
ArtNr CS-CRB002
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Applications
Immunization or labeling (iodination) purposes.
Description
Cancer Antigen 15-3 Breast Tumor Marker is an isoform of Mucin 1 (MUC1). MUC1 belongs to the Mucin family and is a membrane bound, glycosylated phosphoprotein. MUC1 is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa Variable Number Tandem Repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. MUC1 serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined.
Formulation
Liquid in PBS pH 7.4 + 0.1% Sodium Azide. Precaution: Sodium Azide is a poisonous and hazardous substance which should be handled by trained staff only.
Storage and Stability
Store at -20C. Avoid repeated freeze-thaw cycles .
GeneID
4582
Source
Human Ascites fluid
Purity
95% (Iodination grade) as determined by SDS PAGE analysis
Menge: 25 KU
Lieferbar: In stock
Listenpreis: 665,44 €
Rabatt: -10,0%
Preis: 598,90 €
Sie sparen: 66,54 €
lieferbar

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Arbeitsanleitung

CS-CRB002.pdf