Recombinant Human BMP-13

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Human
Menge 1.0 mg
Host E.coli
ArtNr CS-CRB103C
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Description
BMPs (bone morphogenetic proteins) belong to the TGF-b superfamily of structurally related signaling proteins. These ligands mediate numerous physiological processes. BMPs initiate, promote and maintain cartilage and bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Expression of BMP-13 has been found in the hypertrophic chondrocytes of ossifying long bone centers. Recombinant human BMP-13/CDMP-2 is a 27 kDa homodimeric disulfide-linked protein consisting of two 120 amino acids polypeptide chains.
Formulation
Lyophilized without additives.
Reconstitution
Centrifuge vial prior to opening. The human BMP-13 should be reconstituted in water containing BSA (50 ug BSA per 1 ug protein) to a concentration of 0.1-1.0 mg/ml. This solution can be diluted in water or other buffer solutions and stored for 1 week at 2-4C or at -20C for future use. Note: Due to solubility reasons, the protein should be kept at a low pH.
Storage and Stability
The lyophilized protein is best stored desiccated below 0C. Reconstituted protein should be stored in working aliquots at -20C. Avoid repeated freeze-thaw cycles.
Source
E. coli
Molecular Weight
27.0 kDa
Purity
>95% as determined by SDS-PAGE analysis.
Endotoxin Level
<0.1 ng per ug of BMP-13.
Biological Activity
Determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells is in the range of 2-3 ug/ml.
Menge: 1.0 mg
Lieferbar: In stock
Listenpreis: 3.583,09 €
Preis: 3.583,09 €
lieferbar

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