CD31/PECAM-1 (aa 625-739) Human Recombinant

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Human
Menge 2 ug
Host E.coli
ArtNr CS-CRC140A
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Description
Human Recombinant CD31/PECAM1 comprises aa 625-739 and is purified by proprietary chromatographic techniques. CD31 is a glycoprotein expressed on endothelial cells, platelets, macrophages and Kupffer cells, granulocytes, T / NK cells, lymphocytes, megakaryocytes, fibroblasts, osteoclasts, and neutrophils. In humans, the gene encoding CD31 is found on chromosome 17. CD31 is also called PECAM-1 for platelet endothelial cell adhesion molecule. It plays a key role in removing aged neutrophils from the body. Both neutrophils and macrophages express CD31 on their membranes, and during the testing process, these CD31 molecules bind the two cells together. If the neutrophil is healthy, it will send a signal to the macrophage, and the CD31 molecules will detach. CD31 is also expressed in certain tumors, including epithelioid hemangioendothelioma, epithelioid sarcoma-like hemangioendothelioma, other vascular tumors, histiocytic malignancies, and plasmacytomas. It is rarely found in some sarcomas and carcinomas.
Formulation
Liquid in 50 mM Tris-Acetate, pH 7.5 + 1 mM EDTA + 20% Glycerol.
Storage and Stability
Store at -80C. For multiple use, aliquot and freeze at -80C. Stable for 1 year. Avoid repeated freeze-thaw cycles.
Concentration
0.1 mg/ml
GeneID
5175
Source
E. coli
Endotoxin Level
<0.1 ng/ug of protein.
Menge: 2 ug
Lieferbar: Out of stock
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Arbeitsanleitung

CS-CRC140A.pdf