Recombinant Human Centromere Protein A His

Hersteller Cell Sciences
Typ Proteins
Specific against Human
Menge 5 ug
ArtNr CS-CRC151A
eClass 6.1 34160400
eClass 9.0 42020190
Centromere proteins are a group of proteins which form and/or mediate the function of centromeres, the central structures of chromosomes to which spindle fibers/microtubuli attach and pull the chromosomes apart in cell division. Currently, 9 centromere proteins are known and designated CENPA to CENP-I. Most of the centromere proteins are targets of autoantibodies, the anti-centromere antibodies. CENPA is another important centromeric autoantigen in addition to CENPB: it has a molecular weight of approx. 20 kDa and is incorporated into centromeric chromatin due to its histone-like properties. CENPA antibodies are an important marker for correct diagnosis of Scleroderma / CREST syndrome in CENPB-autoantibody negative patients. CENPA Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a MW = 17, 015 Dalton. CENPA is expressed with a -6x His tag and purified by proprietary chromatographic techniques.
Sterile filtered liquid in 20 mM HEPES, pH 8.0 + 100 mM sodium chloride + 6 M urea
Storage and Stability
Store at 2-4C for up to 4 weeks or in working aliquots at -20C for longer storage. Avoid repeated freeze-thaw cycles.
Sf9 cells
Molecular Weight
17.015 kDa
> 90% as determined by SDS-PAGE analysis
Menge: 5 ug
Lieferbar: In stock
Listenpreis: 226,60 €
Preis: 226,60 €


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