Recombinant Human Centromere Protein B His

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Human
Menge 1.0 mg
Host Insect
ArtNr CS-CRC152C
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Description
Centromere proteins are a group of proteins which form and/or mediate the function of centromeres, the central structures of chromosomes to which spindle fibers/microtubuli attach and pull the chromosomes apart in cell division. Currently, 9 centromere proteins are known and designated CENPA to CENP-I. Most of the centromere proteins are targets of autoantibodies, the anti-centromere antibodies. CENPB is the most important of the centromeric autoantigens: it has a molecular weight of approx. 66 kDa and plays an important role in the formation of the centromeric chromatin. CENPB antibodies are present in the sera of up to 80% of patients with CREST syndrome. CENPB Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a MW = 65, 940 Dalton. CENPB is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques.
Formulation
Sterile filtered liquid in 20 mM HEPES, pH 7.6 + 250 mM sodium chloride + 20% glycerol
Storage and Stability
Store at 2-4C for up to 4 weeks or in working aliquots at -20C for longer storage. Avoid repeated freeze-thaw cycles.
GeneID
1059
Source
Sf9 insect cells
Molecular Weight
65.94 kDa
Purity
> 90% as determined by SDS-PAGE analysis
Protein Accession No
NP_001801
Endotoxin Level
< 0.1 ng/ug of CENPB
Menge: 1.0 mg
Lieferbar: In stock
Listenpreis: 5.524,27 €
Preis: 5.524,27 €
lieferbar

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