Native Human Complement Component C4c

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Human
Menge 200 ug
Host Human
ArtNr CS-CRC165A
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Description
Native Human Complement Component C4c. Complement C4c is a degradation product of C4b which is cleaved by C4b/C3b inactivator to yield C4d and C4c. Complement C4c interacts with C1 and C2 to form C3 convertase of the classic activation pathway. Systemic lupus erythematosus (SLE) is often associated with congenital C4deficiency. Reduced levels of components of the classic pathway (C1, C2, C4, C3) are common after such activation, e.g. in SLE, acute serum sickness and conditions associated with circulating immune complexes.
Formulation
Sterile filtered clear solution of Sodium Phosphate Buffer, pH 7.0, + 0.15 M NaCl, + 0.09% NaN3.
Storage and Stability
Stable at 2-4C for 1 week. For long term storage, aliquot and freeze at -20C. Avoid repeated freeze-thaw cycles.
GeneID
721 (Complement Component C4b)
Source
Human Plasma
Molecular Weight
210 kDa
Purity
>99.0%
Endotoxin Level
< 0.1 ng/ug of protein.
Menge: 200 ug
Lieferbar: Out of stock
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