Recombinant Human Crystallin Alpha A

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Human
Menge 20 ug
Host E.coli
ArtNr CS-CRC167A
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Description
Alpha crystallins are composed of two gene products, alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein(sHSP also known as the HSP20). They act as molecular chaperones and hold them in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits, the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional function of a-crystallins are an autokinase activity and participation in the intracellular architecture. The expression of alpha-A is preferentially restricted to the lens cell. Recombinant Human CRYAA is a single, non-glycosylated polypeptide chain containing 173 amino acids and purified by proprietary chromatographic techniques.
Formulation
Sterile filtered liquid in 20 mM Tris-HCl, pH 7.5, + 50 mM NaCl + 1 mM EDTA
Storage and Stability
Store at 2-4C for up to 4 weeks or in working aliquots at -20C for longer storage. Add a carrier protein (0.1% HSA or BSA) as a stabilizer for long term storage. Please note that the addition of any carrier protein into this product may produce unwanted endotoxin. This depends upon the particular application employed. Avoid repeated freeze-thaw cycles.
Concentration
1 mg/ml
GeneID
1409
Source
E. coli
Molecular Weight
19.91 kDa
Purity
> 95% as determined by RP-HPLC and SDS-PAGE analyses
Endotoxin Level
< 0.1 ng/ug of CRYAA
AA Sequence
MDVTIQHPWF KRTLGPFYPS RLFDQFFGEG LFEYDLLPFL SSTISPYYRQ SLFRTVLDSG ISEVRSDRDK FVIFLDVKHF SPEDLTVKVQ DDFVEIHGKH NERQDDHGYI SREFHRRYRL PSNVDQSALS CSLSADGMLT FCGPKIQTGL DATHAERAIP VSREEKPTSA PSS
Menge: 20 ug
Lieferbar: In stock
Listenpreis: 206,00 €
Rabatt: -10,0%
Preis: 185,40 €
Sie sparen: 20,60 €
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Arbeitsanleitung

CS-CRC167A.pdf