Recombinant Human Crystallin Alpha B

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Human
Menge 1.0 mg
Host E.coli
ArtNr CS-CRC168C
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Description
Alpha Crystallins are composed of two gene products, alpha-A and alpha-B, for acidic and basic, respectively. Alpha Crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20). They act as molecular chaperones and hold them in in large soluble aggregates. These heterogeneous aggregates consist of 30-40 subunits, the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional function of Alpha Crystallins have autokinase activity and participate in intracellular architecture. Alpha-B is expressed widely in many tissues and organs and occurs in many neurological diseases. Recombinant human Crystallin Alpha B is a single, non-glycosylated polypeptide chain containing 175 amino acids and purified by proprietary chromatographic techniques.
Formulation
Sterile filtered liquid in 20 mM Tris-HCl, pH 7.5, + 50 mM NaCl + 1 mM EDTA
Storage and Stability
Store at 2-4C for up to 4 weeks or in working aliquots at -20C for longer storage. Add a carrier protein (0.1% HSA or BSA) as a stabilizer for long term storage. Please note that the addition of any carrier protein into this product may produce unwanted endotoxin. This depends upon the particular application employed. Avoid repeated freeze-thaw cycles.
Concentration
1 mg/ml
GeneID
1410
Source
E. coli
Molecular Weight
20.16 kDa
Purity
> 95% as determined by RP-HPLC and SDS-PAGE analyses
Endotoxin Level
< 0.1 ng/ug of CRYAB
AA Sequence
MDIAIHHPWI RRPFFPFHSP SRLFDQFFGE HLLESDLFPT STSLSPFYLR PPSFLRAPSW FDTGLSEMRL EKDRFSVNLD VKHFSPEELK VKVLGDVIEV HGKHEERQDE HGFISREFHR KYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVT AAPKK
Menge: 1.0 mg
Lieferbar: In stock
Listenpreis: 1.763,23 €
Preis: 1.763,23 €
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