Native Human Cystatin C

Hersteller Cell Sciences
Typ Proteins
Specific against Human
Menge 100 ug
Host Human
ArtNr CS-CRC173B
Eclass 6.1 34160400
Eclass 9.0 42020190
Cystatins are a superfamily of cysteine proteinase inhibitors found in both plants and animals. They comprise a group of proteinase inhibitors, widely distributed in tissues and body fluids, and form tight complexes with cysteine proteases such as cathepsin B, H, L and S. Cystatin C, a secreted molecule of this family, is of interest from biochemical, medicine and evolutionary points of view. Cystatin C, with molecular weight of 13260 Da, is composed of 120 amino acids, lacks carbohydrate and has two disulfide bridges located near the carboxyl terminus. Cystatin C is increased in patients with malignant diseases, and is related to the insufficiency of renal function and appears to be a better marker than creatinine. On the other hand, low levels of cystatin C involve cause the breakdown of the elastic laminae and, subsequently, the atherosclerosis and abdominal aortic aneurysm.
Lyophilized from 0.02 M NH4HCO3. May contain traces of buffer salts.
Centrifuge vial prior to opening. Add 0.02 M NH4HCO3 buffer to the vial to fully solubilize the protein.
Storage and Stability
Human Cystatin-C although stable at 4C for 1 week, should be stored at -15C. Please avoid freeze-thaw cycles.
Human urine
Greater than 96% as determined by SDS PAGE.
Endotoxin Level
< 0.1 ng/ug of Cystatin C
Menge: 100 ug
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