Recombinant Human EFNA4 GST

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Human
Menge 10 ug
Host E.coli
ArtNr CS-CRE111C
Eclass 6.1 34160400
Eclass 9.0 42020190
Lieferbar
Description
Ephrin A4 is a member of the ephrin (EPH) family. Ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases. Based upon their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are attached to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Class A ephrins are linked to the membrane by a GPI linkage and bind primarily to EphA receptors, Class B ephrins contain a membrane-spanning region and bind primarily to EphB receptors. Both ephrins and Eph receptors are largely expressed throughout the ectoderm, mesoderm, and endoderm of vertebrate embryos. EFNA binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variations which encode different isoforms were identified through sequence analysis. During development the Eph receptor and their membrane-attached ligands, ephrins, show diverse expression patterns. The ephrins and EPH-related receptors mediate developmental events, principally in the nervous system and in erythropoiesis. The critical roles of Eph and ephrins during development imply involvement of these genes in congenital disorders affecting the nervous system and other tissues. Ephrins and Eph receptors are possibly involved in carcinogenesis. Ephrin A4 Human Recombinant full length protein expressed in, E. coli, , shows a 46 kDa SDS-PAGE (Including GST tag). The Ephrin A4 is purified by proprietary chromatographic techniques.
Formulation
Sterile filtered liquid in 50 mM Tris-Acetate, pH 7.5 + 1 mM EDTA + 20% glycerol
Storage and Stability
Stable for 1 year at -20C to -80C. Avoid repeated freeze-thaw cycles.
Concentration
0.1 mg/ml
GeneID
1945
Source
E. coli
Molecular Weight
46 kDa

Arbeitsanleitung

CS-CRE111C.pdf

Menge: 10 ug
Lieferbar: In stock
Listenpreis: 907,91 €
Preis: 907,91 €
lieferbar

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Arne Pelz

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