Recombinant Human Ephrin B3

Hersteller Cell Sciences
Typ Proteins
Specific against Human
Menge 10 ug
Host E.coli
ArtNr CS-CRE113C
eClass 6.1 34160400
eClass 9.0 42020190
Recombinant Human Ephrin-B3 is comprised of aa 135-341 of the full length protein and is purified by proprietary chromatographic techniques. Ephrin-B3 Ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases. The Eph Receptors characteristically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. Based upon their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are attached to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Class A ephrins are linked to the membrane by a GPI linkage and bind primarily to EphA receptors, Class B ephrins contain a membrane-spanning region and bind primarily to EphB receptors. Both ephrins and Eph receptors are largely expressed throughout the ectoderm, mesoderm, and endoderm of vertebrate embryos. Ephrin-B3 is a member of the ephrin gene family and is significant in brain development and maintenance. Since levels of Ephrin-B3 expression are particularly high in several forebrain subregions compared to other brain subregions, it may play a key role in forebrain function.
Sterile filtered clear solution of 50 mM Tris-acetate Buffer, pH 7.5, + 1 mM EDTA + 20% glycerol
Storage and Stability
Store at -80C. Stable for 1 year. For multiple use, aliquot and freeze at -80C. Avoid repeated freeze-thaw cycles.
E. coli
Molecular Weight
47 kDa by SDS-PAGE
Endotoxin Level
< 0.1 ng/ug of protein.
Menge: 10 ug
Lieferbar: Out of stock
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