Recombinant Human CXCL5/ENA78

Hersteller Cell Sciences
Kategorie Produkte / Proteins
Typ Proteins
Specific against Human
Menge 5 ug
Host E.coli
ArtNr CS-CRE300A
Eclass 6.1 34160400
Eclass 9.0 42020190
Human ENA-78/CXCL5(5-78a.a.) Epithelial cell-derived neutrophil-activating peptide 78 (ENA-78) is a member of the CXC subfamily of chemokines that has the Glu-Leu-Arg (ELR) motif preceding the CXC motif. Similar to other ELR containing CXC chemokines, ENA-78 is a potent neutrophil chemoattractant and activator. Proteolysis of ENA-78 with cathepsin G and chymotrypsin have yielded N-terminally truncated variants with increased biological activities. ENA-80 and ENA-74 represent truncated recombinant ENA-78 variants missing 8 and 4 aa residues, respectively, from the N-terminus. Recombinant ENA-80 and ENA-74 have been shown to have increased potency in neutrophil chemotaxis and myeloperoxidase and elastase release assays.
Lyophilized from a 0.2um filtered concentrated (1.0 mg/ml) solution in 20mM PB, pH 7.4, 50mM NaCl.
Centrifuge vial prior to opening. We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20C. Further dilutions should be made in appropriate buffered solutions.
Storage and Stability
This lyophilized preparation is stable at 2-8C, but should be kept at -20C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -80C. Avoid repeated freeze/thaw cycles.
E. coli
Molecular Weight
8.0 kDa, a single non-glycosylated polypeptide chain containing 74 amino acids.
>97% by SDS-PAGE and HPLC analyses.
Endotoxin Level
Less than 1EU/ug of rHuENA-78/CXCL5 as determined by LAL method.
Biological Activity
Fully biologically active when compared to standard. Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 5.0-10.0 ng/ml.
AA Sequence
Menge: 5 ug
Lieferbar: In stock
Listenpreis: 206,00 €
Rabatt: -10,0%
Preis: 185,40 €
Sie sparen: 20,60 €

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