Recombinant Mouse BAX (aa 38-171)

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Mouse
Menge 1.0 mg
Host E.coli
ArtNr CS-CRB112C
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Description
Recombinant Mouse Bcl-2-associated X protein (Bax) comprising aa 38-171 is a single, non-glycosylated polypeptide chain purified by proprietary chromatographic techniques. Bax belongs to the Bcl-2 protein family. It is a pro-apoptotic Bcl-2 protein containing BH1, BH2 and BH3 domains. Bax accelerates programmed cell death by binding to and antagonizing the apoptosis repressor bcl2 or its adenovirus homolog e1b 19k protein. Bax induces the release of cytochrome c, activation of casp3, and thereby apoptosis. Bax is expressed in a wide variety of tissues, with highest levels in the testis and ovary. Tumor suppressor protein p53 upregulates the expression of BAX. Bax has been shown to be involved in p53-mediated apoptosis.
Formulation
Sterile filtered colorless solution containing 10 mM Tris-HCl, pH 8, + 1 mM EDTA + 250 mM NaCl.
Storage and Stability
Store desiccated at -80C. For multiple use, aliquot and freeze working stocks at -80C. Stable for 1 year. Avoid repeated freeze-thaw cycles.
GeneID
12028
Source
E. coli
Purity
>95% by RP-HPLC and SDS-PAGE
Endotoxin Level
<0.1 ng/ug of protein
Menge: 1.0 mg
Lieferbar: In stock
Listenpreis: 6.974,08 €
Preis: 6.974,08 €
lieferbar

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