Recombinant Mouse C5a His

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Mouse
Menge 100 ug
Host E.coli
ArtNr CS-CRC238B
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Description
Mouse complement C5a is a 77-amino acid peptide generated during complement activation from the alpha-chain of complement C5. Mouse C5a shares 60% and 82% amino acid sequence identity to human and rat C5a, respectively. C5a binds to a signaling G-protein coupled receptor (GPCR) (C5aR/CD88), inducing neutrophil chemotaxis and endothelial cell activation. It also triggers an oxidative burst in macrophages and neutrophils, and induces release of histamine in basophils and mast cells. The recombinant protein contains an N-terminal His-Tag sequence.
Formulation
Lyophilized with no additives
Reconstitution
Centrifuge vial prior to opening. Reconstitute to a concentration of 1.0 mg/ml in ice-cold water containing 2.5 mg/ml BSA. The solution should be aliquotted and immediately stored at -80C for future use. Avoid repeated freeze-thaw cycles as they can result in some loss of activity.
Storage and Stability
Store at -20C or -80C as supplied. Stable for at least 1 year. After reconstitution, aliquot and store at-80C. Avoid repeated freeze-thaw cycles.
GeneID
15139
Source
E. coli
Molecular Weight
9 kDa
Purity
>95% by SDS-PAGE.
Endotoxin Level
<0.1 ng per ug of C5a
Biological Activity
Recombinant Mouse C5a is as active as that of serum derived C5a based on enzyme release assay of myeloperoxidase. A typical lot has an ED50 = 1-3 nM.
Menge: 100 ug
Lieferbar: In stock
Listenpreis: 1.654,05 €
Preis: 1.654,05 €
lieferbar

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