STAG3 Antibody

ELISA, WB; WB:1:500-1:3000

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Synthesized peptide derived from C-terminal of human STAG3.

Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I By similarity.

Pezzi N., FASEB J. 14:581-592(2000).
The German cDNA consortium, Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Prieto I., EMBO Rep. 3:543-550(2002).

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Cell Biology

Synthesized peptide derived from C-terminal of Human STAG3.