TP53INP2 Antibody

ELISA, IHC, IF; IHC:1:50-1:100, IF:1:100-1:500

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Synthesized peptide derived from internal of human TP53INP2.

Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.

Baumgartner B.G., Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
Deloukas P., Nature 414:865-871(2001).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Cell Biology

Synthesized peptide derived from internal of Human TP53INP2.