PTPRM Antibody

Polyclonal Antibody

PTPRM

tibody, hR PTPu antibody, Protein tyrosine phosphatase mu antibody, Protein tyrosine phosphatase mu precursor antibody, Protein tyrosine phosphatase receptor type M antibody, Protein tyrosine phosphatase receptor type mu polypeptide antibody, Protein-tyrosine phosphatase mu antibody, PTPRL1 antibody, Ptprm antibody, PTPRM protein antibody, PTPRM_HUMAN antibody, R PTP mu antibody, R-PTP-mu antibody, Receptor type tyrosine protein phosphatase mu antibody, Receptor-type tyrosine-protein phosphatase mu antibody, RPTP mu antibody, RPTPM antibody, RPTPU antibody

Synthetic peptide of human PTPRM

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.

Antigen Affinity Purified

Signal Transduction

Synthetic peptide of Human PTPRM