MLF1 Antibody

ArtNr	CSB-PA583476
Hersteller	Cusabio
Menge	100 ul
Kategorie	Oncology Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Sarcoma Adenocarcinoma Western Blot ELISA Primary Antibodies By Organ Heart & Blood Cancer Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Hls7 antibody,MLF1 antibody,MLF1_HUMAN antibody,Myelodysplasia myeloid leukemia factor 1 antibody,Myelodysplasia-myeloid leukemia factor 1 antibody,Myeloid leukemia factor 1 antibody,myeloid leukemia factor 1 variant 1 antibody,myeloid leukemia factor 1 variant 2 antibody,myeloid leukemia factor 1 variant 3 antibody
Similar products	Myelodysplasia-myeloid leukemia factor 1, Myeloid leukemia factor 1
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB; WB:1:500-1:3000
Manufacturer - Targets	MLF1
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	Hls7 antibody, MLF1 antibody, MLF1_HUMAN antibody, Myelodysplasia myeloid leukemia factor 1 antibody, Myelodysplasia-myeloid leukemia factor 1 antibody, Myeloid leukemia factor 1 antibody, myeloid leukemia factor 1 variant 1 antibody, myeloid leukemia factor 1 variant 2 antibody, myeloid leukemia factor 1 variant 3 antibody
Immunogen Species	Human
Immunogen	Synthesized peptide derived from internal of human MLF1.
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:3000
Background	Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus. Yoneda-Kato N., Oncogene 12:265-275(1996) [PubMed: 8570204]. Hanissian S.H., Oncogene 23:3700-3707(2004) [PubMed: 15116101]. Yoneda-Kato N., EMBO J. 24:1739-1749(2005) [PubMed: 15861129].
Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
General Research Areas	Cardiovascular
Initial Research Areas	Cardiovascular
Antigen Species	Human
Antigen	Synthesized peptide derived from internal of Human MLF1.
Clonality	Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

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Lieferung vsl. bis 25.12.2025

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