PTEN Antibody

ArtNr	CSB-PA018964KA01HU
Hersteller	Cusabio
Menge	100 ul
Kategorie	Oncology Neuroscience Metabolism Diabetes Molecular Targets for Neuroscience Targets for Rodent Neurosciences Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Adenocarcinoma Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	10q23del antibody,BZS antibody,DEC antibody,GLM2 antibody,MGC11227 antibody,MHAM antibody,MMAC1 antibody,MMAC1 phosphatase and tensin homolog deleted on chromosome 10 antibody,Mutated in multiple advanced cancers 1 antibody,Phosphatase and tensin homolog antibody,Phosphatase and tensin like protein antibody,Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN antibody,Pten antibody,PTEN_HUMAN antibody,PTEN1 antibody,TEP1 antibody
Similar products	PTEN, TEP1, 10q23del, BZS, MHAM, MMAC1, PTEN1, DEC, GLM2
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB, IHC; WB:1:500-1:2000, IHC:1:50-1:200
Manufacturer - Targets	PTEN
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	10q23del antibody, BZS antibody, DEC antibody, GLM2 antibody, MGC11227 antibody, MHAM antibody, MMAC1 antibody, MMAC1 phosphatase and tensin homolog deleted on chromosome 10 antibody, Mutated in multiple advanced cancers 1 antibody, Phosphatase and tensin homolog antibody, Phosphatase and tensin like protein antibody, Phosphatidylinositol 3, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN antibody, Pten antibody, PTEN_HUMAN antibody, PTEN1 antibody, TEP1 antibody
Immunogen Species	Human
Immunogen	Recombinant protein of human PTEN
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:2000 IHC:1:50-1:200
Background	PTEN (phosphatase and tensin homologue deleted on chromosome ten), also referred to as MMAC (mutated in multiple advanced cancers) phosphatase, is a tumor suppressor implicated in a wide variety of human cancers. PTEN encodes a 403 amino acid polypeptide originally described as a dual-specificity protein phosphatase. The main substrates of PTEN are inositol phospholipids generated by the activation of the phosphoinositide 3-kinase (PI3K). PTEN is a major negative regulator of the PI3K/Akt signaling pathway. PTEN possesses a carboxy-terminal, noncatalytic regulatory domain with three phosphorylation sites (Ser380, Thr382, and Thr383) that regulate PTEN stability and may affect its biological activity. PTEN regulates p53 protein levels and activityand is involved in G protein-coupled signaling during chemotaxis.
Buffer	Store at -20°C or -80°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method	Affinity-chromatography purified
General Research Areas	Cell Biology
Initial Research Areas	Cell Biology
Antigen Species	Human
Antigen	Recombinant protein of Human PTEN
Clonality	Polyclonal

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Menge: 100 ul

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Lieferung vsl. bis 25.12.2025

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