Phospho-MAP2K2 (Thr394) Antibody

Polyclonal Antibody

MAP2K2

Cardiofaciocutaneous syndrome antibody, CFC syndrome antibody, CFC4 antibody, Dual specificity mitogen activated protein kinase kinase 2 antibody, Dual specificity mitogen-activated protein kinase kinase 2 antibody, ERK activator kinase 2 antibody, FLJ26075 antibody, MAP kinase kinase 2 antibody, map2k2 antibody, MAPK / ERK kinase 2 antibody, MAPK/ERK kinase 2 antibody, MAPKK 2 antibody, MAPKK2 antibody, MEK 2 antibody, MEK2 antibody, Microtubule associated protein kinase kinase 2 antibody, Mitogen activated protein kinase kinase 2 antibody, Mitogen activated protein kinase kinase 2 p45 antibody, MKK 2 antibody, MKK2 antibody, MP2K2_HUMAN antibody, OTTHUMP00000165826 antibody, OTTHUMP00000165827 antibody, PRKMK 2 antibody, PRKMK2 antibody

Peptide sequence around phosphorylation site of threonine 394 (P-G-T(p)-P-T) derived from Human MEK-2.

Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases.

Crews C M, et al. (1992) Science. 258:478-480.
Alessi D R, et al. (1994) EMBO J. 13:1610-1619.
Rosen L B, et al. (1994) Neuron. 12:1207-1221.
Cowley S, et al. (1994) Cell. 77:841-852.

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Signal Transduction

Peptide sequence around phosphorylation site of threonine 394 (P-G-T(p)-P-T) derived from Human MEK-2.