MAP2K4 (Ab-261) Antibody

Polyclonal Antibody

MAP2K4

c Jun N terminal kinase kinase 1 antibody, C-JUN N-terminal kinase kinase 1 antibody, Dual specificity mitogen activated protein kinase kinase 4 antibody, Dual specificity mitogen-activated protein kinase kinase 4 antibody, JNK Activated Kinase 1 antibody, JNK activating kinase 1 antibody, JNK-activating kinase 1 antibody, JNKK antibody, JNKK1 antibody, MAP kinase kinase 4 antibody, Map2k4 antibody, MAPK ERK kinase 4 antibody, MAPK/ERK kinase 4 antibody, MAPKK 4 antibody, MAPKK4 antibody, MEK 4 antibody, MEK4 antibody, Mitogen activated protein kinase kinase 4 antibody, MKK 4 antibody, MKK4 antibody, MP2K4_HUMAN antibody, PRKMK4 antibody, SAPK ERK kinase 1 antibody, SAPK/ERK kinase 1 antibody, SAPKK 1 antibody, SAPKK1 antibody, SEK1 antibody, SERK1 antibody, SKK1 antibody, Stress activated protein kinase kinase 1 antibody

Peptide sequence around aa.259ca.263 (A-K-T-R-D) derived from Human SEK1/MKK4.

Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).

Wang W, et al. (2002) Mol Cell Biol, 22(10): 3389-403.
Leung IW, et al. (2001)J Biol Chem, 276(3): 1961-7.

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Signal Transduction

Peptide sequence around aa.259~263 (A-K-T-R-D) derived from Human SEK1/MKK4.