6H05 (trifluoroacetate)

Hersteller MedChem Express
Kategorie
Typ Inhibitors
Specific against other
Menge 5mg
ArtNr HY-12408A-5mg
Eclass 6.1 30220300
Eclass 9.0 32160605
Lieferbar
Synonyms
K-Ras inhibitor
Purity
>98%
MW
5901425
Formula
C22H31ClF3N3O4S3
Solubility
DMSO: >= 51 mg/mL
Biological Description
6H05 trifluoroacetate is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C).
IC50 value:
Target: K-Ras G12C
6H05 gives the greatest degree of modification, which allosterically modifies the oncogenic G12C mutant of highly homologous protein H-Ras without affecting wild-type K-Ras [1]. 6H05 can be used as an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors [2].
Menge: 5mg
Lieferbar: In stock
Listenpreis: 212,86 €
Preis: 212,86 €
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