D-Luciferin (sodium salt)

Hersteller MedChem Express
Kategorie
Typ Inhibitors
Specific against other
Menge 10mM/1mL
ArtNr HY-12591-10mM
Eclass 6.1 30220300
Eclass 9.0 32160605
Lieferbar
Alternative_Names
D-(-)-Luciferin sodium salt, Firefly luciferin sodium salt
CAS
103404-75-7
MWt
302.3047
Formula
C11H7N2NaO3S2
Solubility
H2O
Clinical_Information
No Development Reported
Pathway
Others
Target
Others
Biological Activity
D-Luciferin sodium salt is the substrate of luciferases that catalyze the production of light in bioluminescent insects.
In Vitro: D-luciferin is the natural substrate of the enzyme luciferase (Luc), that catalyzes the production of the typical yellowgreen light of fireflies.The present review covers the synthesis of D-luciferin and derivatives or analogues that are substrates or inhibitors of the luciferase from the American firefly Photinus pyralis, the enzyme more frequently used in techniques of in vitro and optical imaging[1].
In Vivo: Bioluminescence imaging (BLI) using the firefly luciferase (Fluc) as a reporter gene and D-luciferin as a substrate is currently the most widely employed technique. The total signal intensity is plotted against the time after D-luciferin injection to generate a time-intensity curve. In addition to the peak signal, the signals at fixed time points (5, 10, 15, and 20?min) after D-luciferin injection are determined as alternatives to the peak signal. The signal in a given time-intensity curve is normalized for the peak signal in the curve to represent the pattern of temporal changes after D-luciferin injection[2].
Menge: 10mM/1mL
Lieferbar: In stock
Listenpreis: 103,57 €
Rabatt: -10,0%
Preis: 93,21 €
Sie sparen: 10,36 €
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