Trimethobenzamide hydrochloride

Hersteller MedChem Express
Kategorie
Typ Inhibitors
Specific against other
Menge 500mg
ArtNr HY-12751A-500mg
eClass 6.1 30220300
eClass 9.0 32160605
Lieferbar
Alternative names
Ro 2-9578
CAS
554-92-7
Biological activity
Trimethobenzamide hydrochloride is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.
IC50 & Target: D2 receptor[1]
In Vitro: Trimethobenzamide is a (non-phenothiazine) benzamide antiemetic that acts centrally to block D2 receptors, thereby inhibiting the medullary chemoreceptor trigger zone by blocking emetic impulses to the vomiting center[1].
In Vivo: The oral bioavailability of Trimethobenzamide is 60% to 100%. The time to peak is about 45 minutes after oral administration and; Intramuscular (I.M.) administration about 30 minutes after intramuscular administration[1].
MW
424.91836
Formula
C21H29ClN2O5
Smiles
O=C(NCC1=CC=C(OCCN(C)C)C=C1)C2=CC(OC)=C(OC)C(OC)=C2.Cl
Solubility
DMSO: >= 100 mg/mL
Clinical phase
Launched
Pathway
GPCR/G Protein, Neuronal Signaling
Target
Dopamine Receptor , Dopamine Receptor
Free  Sample
Available in quantities of 0, 5mg-1mg. Three different samples per customer per year!
Menge: 500mg
Lieferbar: In stock
Listenpreis: 249,29 €
Rabatt: -10,0%
Preis: 224,36 €
Sie sparen: 24,93 €
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