PTACH

Hersteller MedChem Express
Kategorie
Typ Inhibitors
Specific against other
Menge 10mM/1mL
ArtNr HY-12954-10mM
Eclass 6.1 30220300
Eclass 9.0 32160605
Lieferbar
Alternative_Names
NCH-51
CAS
848354-66-5
MWt
390.5627
Formula
C20H26N2O2S2
Solubility
10 mM in DMSO
Clinical_Information
No Development Reported
Pathway
Epigenetics, Cell Cycle/DNA Damage
Target
HDAC, HDAC
Biological Activity
PTACH (NCH-51) is a SAHA-based novel inhibitor of human HDAC. PTACH exerts potent growth inhibition against various human cancer cells, with EC50 values ranging from 1 to 10 uM.
IC50 value: 1-10 uM (EC50)
Target: HDAC
in vitro: In cancer cell growth inhibition assay, PTACH shows strong activity. PTACH inhibits various cancer cells with EC50 of 2.3, 9.1, 3.0, 2.6, 1.1, 4.5, 2.4, 5.0, and 4.5 uM for MDA-MB-231 breast cancer, SNB-78 central nervous system, HCT116 colon cancer, NCI-H226 lung cancer, LOX-IMVI melanoma, SK-OV-3 ovarian cancer, RXF-631L renal cancer, St-4 stomach cancer, and DU-145 prostate cancer.
Menge: 10mM/1mL
Lieferbar: In stock
Listenpreis: 153,93 €
Rabatt: -10,0%
Preis: 138,54 €
Sie sparen: 15,39 €
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