PF-04620110

Hersteller MedChem Express
Kategorie
Typ Inhibitors
Specific against other
Menge 100mg
ArtNr HY-13009-100mg
eClass 6.1 30220300
eClass 9.0 32160605
Lieferbar
Synonyms
PF 04620110, PF04620110
CAS No.
1109276-89-2
Purity
>98%
MW
396, 4397
Formula
C21H24N4O4
Solubility
10 mM in DMSO
Clinical Phase
Phase 1
Signalling Pathway
Metabolic Enzyme/Protease
Target
DGAT
Biological Description
PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM. IC50 value: 19 nM [1] Target: DGAT1 PF-04620110 and imipramine (internal standard) were separated using a Hypersil Gold C18 column, with a mixture of acetonitrile and 10 mm ammonium formate (90:10, v/v) as the mobile phase. The ion transitions monitored in positive-ion mode [M + H](+) of multiple-reaction monitoring were m/z 397.0 -260.2 for PF-04620110 and m/z 280.8 - 86.0 for imipramine. The detector response was specific and linear for PF-04620110 at concentrations within the range 0.05-50 ug/mL and the signal-to-noise ratios for the samples were >=10 [2].
Free  Sample
Available in quantities of 0, 5mg-1mg. Three different samples per customer per year!
Menge: 100mg
Lieferbar: In stock
Listenpreis: 811,79 €
Rabatt: -10,0%
Preis: 730,61 €
Sie sparen: 81,18 €
lieferbar

Vergleichen

Angebot anfordern

Fragen zum Produkt?
 
Schließen