PF-04620110

Hersteller MedChem Express
Kategorie Produkte / Inhibitors
Typ Inhibitors
Specific against other
Clon N/A
Menge 10mg
ArtNr HY-13009-10mg
Eclass 6.1 30220300
Eclass 9.0 32160605
Lieferbar
Synonyms
PF 04620110, PF04620110
CAS No.
1109276-89-2
Purity
>98%
MW
3964397
Formula
C21H24N4O4
Solubility
10 mM in DMSO
Biological Description
PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.
IC50 value: 19 nM [1]
Target: DGAT1
PF-04620110 and imipramine (internal standard) were separated using a Hypersil Gold C18 column, with a mixture of acetonitrile and 10 mm ammonium formate (90:10, v/v) as the mobile phase. The ion transitions monitored in positive-ion mode [M + H](+) of multiple-reaction monitoring were m/z 397.0 -260.2 for PF-04620110 and m/z 280.8 - 86.0 for imipramine. The detector response was specific and linear for PF-04620110 at concentrations within the range 0.05-50 ug/mL and the signal-to-noise ratios for the samples were >=10 [2].
Free  Sample
Available in quantities of 0, 5mg-1mg. Three different samples per customer per year!
Menge: 10mg
Lieferbar: In stock
Listenpreis: 177,50 €
Preis: 177,50 €
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