Laquinimod

Hersteller MedChem Express
Kategorie
Typ Inhibitors
Specific against other
Clon N/A
Menge 10mM*1mL (in DMSO)
ArtNr HY-13010-10mM
Eclass 6.1 30220300
Eclass 9.0 32160605
Lieferbar
Synonyms
ABR-215062, ABR 215062, ABR215062
CAS No.
248281-84-7
Purity
>98%
MW
3568029
Formula
C19H17ClN2O3
Solubility
10 mM in DMSO
Biological Description
Laquinimod (ABR-215062) is a potent immunomodulator.
IC50 value:
Target: immunomodulator
Laquinimod is a novel oral drug that is currently being evaluated for the treatment of relapsing-remitting (RR) multiple sclerosis (MS).
Laquinimod has demonstrated significant activity in suppressing experimental autoimmune encephalomyelitis, an animal model of RRMS. In phase I and II clinical trials, the drug was well tolerated, with some hints of efficacy in small numbers of patients with RRMS. While the mechanism of action of the drug is unknown, it likely involves Th1 to Th2/Th3 immune deviation, promotion of the synthesis and release of neurotrophic factors, and other possible neuroprotective effects. A Phase II study of Laquinimod in active lupus arthritis patients is currently ongoing, if successful, will lead to the approval of the first oral immunomodulatory drug for suppressing multiple sclerosis disease activity.
Free  Sample
Available in quantities of 0, 5mg-1mg. Three different samples per customer per year!

Sicherheitsdatenblatt

HY-13010-10mM.pdf

Menge: 10mM*1mL (in DMSO)
Lieferbar: In stock
Listenpreis: 114,29 €
Rabatt: -10,0%
Preis: 102,86 €
Sie sparen: 11,43 €
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