7-xylosyltaxol

Hersteller MedChem Express
Kategorie
Typ Inhibitors
Specific against other
Menge 50mg
ArtNr HY-77574-50mg
eClass 6.1 30220300
eClass 9.0 32160605
Lieferbar
Synonyms
7-Xylosylpaclitaxel, Taxol-7-xyloside
CAS No.
90332-66-4
Purity
>98%
MW
9860208
Formula
C52H59NO18
Solubility
10 mM in DMSO
Biological Description
7-xylosyltaxol(Taxol-7-xyloside) is a taxol (Paclitaxel) derivative; Paclitaxel binds to tubulin and inhibits the disassembly of microtubules.
IC50 Value:
Target: Microtubule/Tubulin
Paclitaxel is a compound extracted from the Pacific yew tree with antineoplastic activity. Paclitaxel also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2). Paclitaxel inhibits DNA synthesis and stimulates the release of tumor necrosis factor-alpha. Paclitaxel induces apoptosis in murine mammary carcinoma MCA-4 and ovarian carcinoma OCA-1 tumors.
Menge: 50mg
Lieferbar: Out of stock
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