Tildipirosin

Hersteller MedChem Express
Kategorie
Typ Inhibitors
Specific against other
Menge 100mg
ArtNr HY-A0071-100mg
eClass 6.1 30220300
eClass 9.0 32160605
Lieferbar
CAS No.
328898-40-4
Purity
>98%
MW
7340178
Formula
C41H71N3O8
Solubility
10 mM in DMSO
Biological Description
Tildipirosin, a long-acting macrolide, has antibiotic activity.
In Vitro: Tildipirosin exhibits the inhibitory effect on C. coli species, and 23 of 31 (74%) isolates have MICs of 8 or 16 ug/mL while 8 of 31 (26%) have MIC >256 ug/mL. MICs against C. jejuni are 8-64 ug/mL. Tildipirosin against S. enterica and E. coli are 2-8 ug/mL[1]. Tildipirosin inhibits the treponeme isolates form from CODD lesions from 19 sheep, with MIC90 of 0.0469 mg/L[3]. The P. multocida B130 clones show the MIC of 0.25 mg/L for tildipirosin. The 10 P. multocida isolates that carry only erm(42) exhibit MIC of 16-32 mg/L for tildipirosin. The single M. haemolytica that harbours only erm(42) shows MIC of 32 mg/L for tildipirosin[4].
In Vivo: The mean percentage of lung consolidation for tildipirosin (4 mg/kg, s.c.)-treated calves is significantly lower than those for tulathromycin-treated and control calves. Metaphylactic administration of tildipirosin to calves 5 days prior to H somni challenge prevents subsequent culture of the pathogen from bronchial secretions and is more effective in minimizing clinical disease and lung lesions than is metaphylactic administration of tulathromycin[2].
Menge: 100mg
Lieferbar: In stock
Listenpreis: 2.510,00 €
Rabatt: -10,0%
Preis: 2.259,00 €
Sie sparen: 251,00 €
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