Recombinant human YOD1 protein

Proteins

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

YOD1 is a highly conserved deubiquitinating enzyme of the ovarian tumor (otubain) family, whose function has yet to be assigned in mammalian cells. YOD1 is a constituent of a multiprotein complex with p97 as its nucleus, suggesting a functional link to a pathway responsible for the dislocation of misfolded proteins from the endoplasmic reticulum. Expression of a YOD1 variant deprived of its deubiquitinating activity imposes a halt on the dislocation reaction, as judged by the stabilization of various dislocation substrates. Recombinant human YOD1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT

Signal Transduction

Human

YOD1, ubiquitin thioesterase OTu1, ubiquitin thioesterase OTu1, DuBA8, OTuD2, PRO0907, RP11-164O23.1, ATGP2019-10ug, ATGP2019-20ug, ATGP2019-50ug, ATGP2019-100ug, ATGP2019-250ug, ATGP2019-500ug, ATGP2019-1mg, ATGP2019-10, ATGP2019-20, ATGP2019-50, ATGP2019-100, ATGP2019-250, ATGP2019-500, ATGP2019-1