Recombinant human TBCC protein

Proteins

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

TBCC (tubulin folding cofactor C) belongs to the TBCC family. It is plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration. Cofactor C is one of four proteins (cofactors A, D, E and C) involved in the pathway leading to correctly folded b-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing b-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/b-tubulin complex; interaction with cofactor C then causes the release of b-tubulin polypeptides. Recombinant human TBCC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT

Cytoskeleton

Human

TBCC, Tubulin-specific chaperone C, CFC, tubulin folding cofactor C, ATGP1673-10ug, ATGP1673-20ug, ATGP1673-50ug, ATGP1673-100ug, ATGP1673-250ug, ATGP1673-500ug, ATGP1673-1mg, ATGP1673-10, ATGP1673-20, ATGP1673-50, ATGP1673-100, ATGP1673-250, ATGP1673-500, ATGP1673-1