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Recombinant human Tmp21/p23 protein

ArtNr NKM-ATGP2253-250ug
Hersteller NKMAX
Menge 250 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 4 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against other
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGS>ISFHLPI NSRKCLREEI HKDLLVTGAY EISDQSGGAG GLRSHLKITD SAGHILYSKE DATKGKFAFT TEDYDMFEVC FESKGTGRIP DQLVILDMKH GVEAKNYEEI AKVEKLKPLE VELRRLEDLS ESIVNDFAYM KKREEEMRDT NESTNTR
Citations Chen F, Hasegawa H, et al. (2006). Nature. 440(7088):1208-12.
Wang H, et al. (2002). J Biol Chem. 277(6):4541-50.
NCBI NP_006818
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Transmembrane emp24 domain-containing protein 10,p23,P24(DELTA),S31I125,S31III125,Tmp-21-I,TMP21
Lieferbar
Manufacturer - Type
Proteins
Manufacturer - Category
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
20 kDa (177aa) confirmed by MALDI-TOF
Description
TMED10 is a member of the EMP24/GP25L/p24 family and a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. Recombinant human TMED10 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by Bradford assay)
Antigen Species
Human
Gene Category
Signal Transduction
Domain
32-185aa
Manufacturer - Search Terms
Tmp21, p23, Transmembrane emp24 domain-containing protein 10, p23, P24(DELTA), S31I125, S31III125, Tmp-21-I, TMP21, ATGP2253-10ug, ATGP2253-20ug, ATGP2253-50ug, ATGP2253-100ug, ATGP2253-250ug, ATGP2253-500ug, ATGP2253-1mg, ATGP2253-10, ATGP2253-20, ATGP2253-50, ATGP2253-100, ATGP2253-250, ATGP2253-500, ATGP2253-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 250 ug
Lieferbar: In stock
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