Antibodies

P2RX1 Antibody

Hersteller ProSci
Kategorie
Typ Antibody Polyclonal
Specific against Human, Canine
Format Liquid
Applikationen WB, IHC, ELISA
Menge 100 ul
Host Rabbit
ArtNr 28-242
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human P2RX1.
Tested Applications
P2RX1 antibody can be used for detection of P2RX1 by ELISA at 1:312500. P2RX1 antibody can be used for detection of P2RX1 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Positive Control 1
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight
45 kDa
Purification
Antibody is purified by protein A chromatography method.
Conjugate
Unconjugated
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration
batch dependent
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store P2RX1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
NCBI Official Symbol
P2RX1
Accession #
NP_002549
Protein GI #
4505545
NCBI Gene ID
5023
User Note
Optimal dilutions for each application to be determined by the researcher.
NCBI Official Full Name
purinergic receptor P2X, ligand-gated ion channel, 1
NCBI Organism
Homo sapiens
Swissprot
P51575
Background
P2RX1 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.
Background References 1
Vial, C., (2006) Biochem. Biophys. Res. Commun. 343 (2), 415-419.

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Menge: 100 ul
Lieferbar: In stock
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