IL-23 p19 Antibody [I 178G]

Hersteller ProSci
Kategorie
Typ Antibody Primary
Specific against Human
Clon I 178G
Isotype IgG2a kappa
Format Liquid
Applikationen WB, ELISA
Menge 100 ug
Host Rat
ArtNr 36-026
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Immunogen
Recombinant human IL-23p19.
Tested Applications
ELISA: (direct or indirect: 1:2, 000-1:10, 000). Western blot: (1:2, 000-1:10, 000 using ECL. Suggested blocking and dilution buffer is TBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature). Optimal conditions should be determined individually for each application.
Specificity
Recognizes human IL-23p19.
Conjugate
Unconjugated
Buffer
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration
1 mg/ml
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C.
NCBI Official Symbol
IL23A
Accession #
42542809
Protein GI #
AAH66268
NCBI Gene ID
51561
User Note
Optimal dilutions for each application to be determined by the researcher.
NCBI Official Full Name
interleukin 23, alpha subunit p19
NCBI Organism
Homo sapiens
Swissprot
Q9NPF7
Background
IL-23p19 associates with IL-12b to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 binds to an heterodimeric receptor complex composed of IL-12RB1 and IL-23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

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Menge: 100 ug
Lieferbar: In stock
Listenpreis: 422,12 €
Preis: 422,12 €
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