IL-23 p19 Antibody [I 338H]

Hersteller ProSci
Kategorie
Typ Antibody Primary
Specific against Human
Clon I 338H
Isotype IgG2a kappa
Format Liquid
Applikationen WB, ELISA
Menge 100 ug
Host Rat
ArtNr 36-027
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Background
IL-23p19 associates with IL-12b to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 binds to an heterodimeric receptor complex composed of IL-12RB1 and IL-23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Research are
Cancer, Inflammation
Alias
Interleukin-23 Subunit p19, Interleukin-23 Subunit alpha, IL-23-A
Conjugate
Unconjugated
Specificity
Recognizes human IL-23p19.
Immunogen
Recombinant human IL-23p19.
Application notes
ELISA: (direct or indirect: 1:2, 000-1:10, 000). Western blot: (1:2, 000-1:10, 000 using ECL. Suggested blocking and dilution buffer is TBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature). Optimal conditions should be determined individually for each application.
Buffer
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Storage
Stable for at least 1 year after receipt when stored at -20˚ C.
Concentration
1 mg/ml
Protein GI #
42542809
Accession #
AAH66268
NCBI Gene ID #
51561
NCBI symbol
IL23A
NCBI full name
interleukin 23, alpha subunit p19
NCBI organism
Homo sapiens
Swissprot #
Q9NPF7

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Menge: 100 ug
Lieferbar: Out of stock
Listenpreis: 422,12 €
Preis: 422,12 €
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