Antibodies

CD137L Antibody [41B436]

Hersteller ProSci
Kategorie
Typ Antibody Primary
Specific against Human
Clon 41B436
Isotype IgG1 kappa
Format Liquid
Applikationen WB, FC, ICC, ELISA
Menge 100 ug
Host Mouse
ArtNr 36-030
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Immunogen
Recombinant human CD137L extracellular domain.
Tested Applications
ELISA: (direct or indirect: 1:500-1:5, 000). Flow Cytometry: (1:1, 000). Immunocytochemistry: (see reference Nr. 2). Western blot: (1:2, 000). Optimal conditions should be determined individually for each application.
Specificity
Recognizes extracellular domain of human CD137L. Does not cross-react with mouse CD137L.
Conjugate
Unconjugated
Buffer
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration
1 mg/ml
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C.
NCBI Official Symbol
TNFSF9
Accession #
728739
Protein GI #
P41273
NCBI Gene ID
8744
User Note
Optimal dilutions for each application to be determined by the researcher.
NCBI Official Full Name
tumor necrosis factor (ligand) superfamily, member 9
NCBI Organism
Homo sapiens
Swissprot
P41273
Background
The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response.

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Menge: 100 ug
Lieferbar: In stock
Listenpreis: 466,67 €
Preis: 466,67 €
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